I've just had my VNF4 Ultra based computer die a second time on me. I get a BIOS post code 50 when I try to boot the box. I bought this computer at the beginning of the year and a few months later, this problem cropped up and I had to RMA my mobo. I got a replacement and it just happened again!
I think the issue is a heat issue, not a USB issue as they would have you believe. I don't live in a very hot area and the mobo has averaged 110F.
Its absolutely ridiculous that this new computer can't handle staying on 24/7. I am likely going to demand my money back. I cannot handle this crap any more.